| Feature | Romexis | Comparable products |
| Scalability | ✔ | ✔ |
| Redundancy | Clustering services | Clustering services |
| User Security | Yes, Active Directory support | Yes, Active Directory support |
| Data Format | DICOM | DICOM |
| DICOM Access Control | ✔ | ✔ |
| Accepts Images from 3rd Party Systems (Storage SCP) | ✔ | ✔ |
| Accepts STL models | Yes, DICOM standard | Yes, DICOM non-standard |
| Query/Retrieve SCP | ✔ | ✔ |
| Worklist and Storage Commitment | Upcoming | ✔ |
| OS | Windows & macOS | Windows only |
| Native 3D CBCT | ✔ | |
| Native CADCAM | ✔ | |
| Native Implant Planning & Guides | ✔ | |
| Other Specialist Modules | Aesthetics, Ceph, 3D Ortho, TMJ, Surgery | |
| One System for All Dental Data | ✔ |